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Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin.
Gene Name: | guanylate cyclase 2C (heat stable enterotoxin receptor) |
Family/Subfamily: | Protein Kinase , Receptor guanylate cyclase |
Synonyms: | GUCY2C, DIAR6, GUC2C, Guanylate Cyclase 2C, HSER, Guanylyl cyclase C, MUCIL, HSTAR, STA receptor, GC-C, Guanylyl cyclase 2C, Intestinal guanylate cyclase, MECIL |
Target Sequences: | NM_004963 NP_004954.2 P25092 |
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