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GUCA2B / Uroguanylin

guanylate cyclase activator 2B (uroguanylin)

Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.

Gene Name: guanylate cyclase activator 2B (uroguanylin)
Synonyms: GUCA2B, Guanylate cyclase activator 2B, UGN, Uroguanylin, GCAP-II
Target Sequences: NM_007102 NP_009033.1 Q16661

Publications (1)

1
UEG Week 2019 Oral Presentations. No authors listed. United European gastroenterology journal. 2019 October;7:10-188. [Full Text Article] [PubMed:32213000] Related Antibodies: LS-C371347.

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
GUCA2B / Uroguanylin (8)
No (8)
6His, N-terminus (1)
GST (1)
His (2)
His-SUMO (1)
Myc-DDK (Flag) (3)
Human (5)
Mouse (2)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Mammalian Cells (1)
Yeast (2)
Purified (1)
GUCA2B / Uroguanylin Protein - Purified recombinant protein GUCA2B was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
11.9 kDa
20 µg/$1,107
GUCA2B / Uroguanylin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Mammalian Cells
6His, N-terminus
100 µg/$1,009; 20 µg/$431; 1 mg/$3,451
GUCA2B / Uroguanylin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
11.9 kDa
20 µg/$150
GUCA2B / Uroguanylin Protein
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Yeast
His
11.5 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
GUCA2B / Uroguanylin Protein
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Yeast
His
11.4 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
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E. coli
His-SUMO
25.5 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
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E. coli
GST
36.8 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
GUCA2B / Uroguanylin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
11.9 kDa
100 µg/$494
Viewing 1-8 of 8 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).