GTF2I / TFII I

general transcription factor IIi

Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.

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Products

Proteins (3)

Type

Recombinant (3)

Target

GTF2I / TFII I (3)

Publications

No (3)

Tag

GST (3)

Species

Human (3)

Source

Wheat Germ Extract (3)

Purification

Purified (3)

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Human GTF2I / TFII I Protein (Recombinant GST) (Full Length) - LS-G28760

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

52.03 kDa

Price:

10 µg/$479; 25 µg/$670

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Human GTF2I / TFII I Protein (Recombinant GST) (Full Length) - LS-G28761

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

136.5 kDa

Price:

2 µg/$439

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Human GTF2I / TFII I Protein (Recombinant GST) (Full Length) - LS-G28762

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

55.88 kDa

Price:

10 µg/$479; 25 µg/$670

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