GTF2A2 / TFIIA

general transcription factor IIA, 2, 12kDa

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

GTF2A2 / TFIIA (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (5)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

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Human GTF2A2 / TFIIA Protein (Recombinant) (Met1-Glu109) - LS-G133627

Source:

E. coli

Tag:

None

Molecular Weight:

16.2kDa

Price:

10 µg/$274; 50 µg/$400; 200 µg/$797; 100 µg/$637; 1 mg/$1,870; 500 µg/$1,424; 5 mg/$2,832; 2 mg/$2,053

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GTF2A2 / TFIIA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116612

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.3 kDa

Price:

100 µg/$494

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Human GTF2A2 / TFIIA Protein (Recombinant His, N-Terminal) - LS-G144402

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

12.3 kDa

Price:

50 µg/$419

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Human GTF2A2 / TFIIA Protein (Recombinant GST) (Full Length) - LS-G28749

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

37.73 kDa

Price:

2 µg/$439

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Human GTF2A2 / TFIIA Protein (Recombinant GST, N-terminus) (aa1-109) - LS-G56309

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human GTF2A2 / TFIIA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79245

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.3 kDa

Price:

20 µg/$150

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