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GSTZ1

glutathione S-transferase zeta 1

GSTZ1 is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

Gene Name: glutathione S-transferase zeta 1
Synonyms: GSTZ1, Glutathione S-aryltransferase, Glutathione S-alkyltransferase, GSTZ1-1, MAAI, Glutathione transferase zeta 1, MAI, Maleylacetoacetate isomerase, Maleylacetone isomerase
Target Sequences: NM_001513 NP_001504.2 O43708

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).