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GSTM4-4 / GSTM4

glutathione S-transferase Mu 4

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.

Gene Name: glutathione S-transferase Mu 4
Synonyms: GSTM4, GTS-Mu2, Glutathione S-transferase M4, GST class-mu 4, GTM4, Glutathione S-transferase mu 4, GST-Mu2, GSTM4-4
Target Sequences: NM_000850 NP_000841.1 Q03013

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Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
GSTM4-4 / GSTM4 (9)
No (9)
GST (1)
GST, N-terminus (2)
His (1)
His-T7 (2)
Myc-DDK (Flag) (3)
Human (7)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (1)
GSTM4-4 / GSTM4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GSTM4-4 / GSTM4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
25.4 kDa
20 µg/$150
GSTM4-4 / GSTM4 Protein - Purified recombinant protein GSTM4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
25.4 kDa
20 µg/$1,107
GSTM4-4 / GSTM4 Protein - Recombinant Glutathione S Transferase Mu 4 By SDS-PAGE
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E. coli
His-T7
27.2 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
GSTM4-4 / GSTM4 Protein - Recombinant  Glutathione S Transferase Mu 4 By SDS-PAGE
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E. coli
His-T7
26.8 kDa
10 µg/$280; 50 µg/$432; 100 µg/$692; 200 µg/$865; 1 mg/$1,966; 500 µg/$1,510; 5 mg/$3,025; 2 mg/$2,153
GSTM4-4 / GSTM4 Protein - 12.5% SDS-PAGE of human GSTM4 stained with Coomassie Blue
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Wheat Germ Extract
GST
49.72 kDa
2 µg/$439
GSTM4-4 / GSTM4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
25.4 kDa
100 µg/$494
GSTM4-4 / GSTM4 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).