GSTM3

glutathione S-transferase mu 3 (brain)

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

GSTM3 (5)

Publications

No (5)

Tag

GST (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human GSTM3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76200

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.4 kDa

Price:

20 µg/$150

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Human GSTM3 Protein (Recombinant His-T7) (aa8-223) - LS-G12555

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.4 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Human GSTM3 Protein (Recombinant GST) (Full Length) - LS-G28741

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

32.89 kDa

Price:

10 µg/$479; 25 µg/$670

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GSTM3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122962

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.4 kDa

Price:

100 µg/$494

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Human GSTM3 Protein (Recombinant His) - LS-G1680

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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