GSTM1

glutathione S-transferase mu 1

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

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Products

ELISA Kits (5)

Type

Development Kit (1)

Sandwich (4)

Target

GSTM1 (5)

Reactivity

Human (2)

Mouse (2)

Rat (1)

Product Group

DevKit DuoPlus (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (3)

Antibody Pair and Standard (1)

Publications

No (5)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (1)

Plasma (5)

Serum (5)

Tissue Homogenates (2)

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Rat GSTM1 (Sandwich ELISA) ELISA Kit - LS-F25220

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$818

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Mouse GSTM1 (Sandwich ELISA) ELISA Kit - LS-F55134

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$818

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Human GSTM1 (Sandwich ELISA) ELISA Kit - LS-F49951

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

2 - 500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$616

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DevKit DuoPlus Mouse GSTM1 ELISA Development Kit - LS-F71482

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

12.5 - 800 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

500 Wells/$1,103; 1000 Wells/$1,614

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Human GSTM1 (Sandwich ELISA) ELISA Kit - LS-F9929

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.13 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$764

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