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GSN / Gelsolin

gelsolin

Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.

Gene Name:	gelsolin
Synonyms:	GSN, ADF, AGEL, Brevin, Actin-depolymerizing factor, Gelsolin precursor, plasma, Gelsolin
Target Sequences:	NM_000177 NP_000168.1 P06396

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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