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Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
Gene Name: | germ cell associated 2 (haspin) |
Family/Subfamily: | Protein Kinase , Haspin |
Synonyms: | GSG2, H-haspin, HASPIN |
Target Sequences: | NM_031965 NP_114171.2 Q8TF76 |
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