GSAP / PION

gamma-secretase activating protein

Regulator of gamma-secretase activity, which specifically activates the production of beta-amyloid protein (beta-amyloid protein 40 and beta-amyloid protein 42), without affecting the cleavage of other gamma-secretase targets such has Notch. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Specifically promotes the gamma-cleavage of APP CTF-alpha (also named APP-CTF) by the gamma-secretase complex to generate beta-amyloid, while it reduces the epsilon-cleavage of APP CTF-alpha, leading to a low production of AICD.

☰ Filters

Products

Proteins (1)

Type

Recombinant (1)

Target

GSAP / PION (1)

Publications

No (1)

Tag

His-T7 (1)

Species

Human (1)

Source

E. coli (1)

Select

Human GSAP / PION Protein (Recombinant His-T7) (aa616-854) - LS-G16363

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.1 kDa

Price:

10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142

Viewing 1-1 of 1 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.