Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

GRN / Granulin

granulin

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Gene Name: granulin
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: GRN, Acrogranin, CLN11, Epithelin precursor, GEP, gp88, Granulin, Granulin-epithelin, Granulins, PC cell-derived growth factor, PCDGF, PEPI, PGRN, Proepithelin, Progranulin
Target Sequences: NM_002087 NP_002078.1 P28799

Publications (1)

1
Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations. Holler CJ, Taylor G, Deng Q, Kukar T. eNeuro. 2017 August;4: [Full Text Article] [PubMed:28828399] [PMC:PMC5562298] Related Antibodies: LS-C154960.

☰ Filters
Products
ELISA Kits (37)
Custom (3)
Development Kit (2)
Sandwich (26)
Sandwich CLIA (6)
GRN / Granulin (37)
Human (14)
Mouse (12)
Rat (6)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
Product Group
DevKit DuoPlus (2)
12 x 8-Well Microstrips (3)
96-Well Microplate (6)
96-Well Strip Plate (25)
Antibody Pair and Standard (2)
No (37)
Breast Milk (1)
Cell Culture Supernatants (13)
Cell Lysates (6)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (29)
Saliva (1)
Serum (30)
Tissue Homogenates (7)
Urine (2)
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
20.58 - 15000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Breast Milk, Cell Culture Supernatants, Plasma, Saliva, Serum, Urine
1 Plate/$795
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GRN / Granulin ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Mouse
62.4 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,302; 1000 Wells/$1,947
GRN / Granulin ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,276; 1000 Wells/$1,903
GRN / Granulin ELISA Kit
Select
Sandwich
Mouse
0.78 - 50 ng/ml
Cell Culture Supernatants, Cell Lysates, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$795
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
4.7 - 300 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$958
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$958
GRN / Granulin ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$685
GRN / Granulin ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
GRN / Granulin ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1560 - 100000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Urine
1 Plate/$717
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
780 - 50000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.078 - 5 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GRN / Granulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GRN / Granulin ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
0.313 - 20 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
GRN / Granulin ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
0.313 - 20 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Viewing 1-25 of 37 product results


Filtered By:
Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).