Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Reasearch Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

GRN / Granulin

granulin

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Gene Name: granulin
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: GRN, Acrogranin, CLN11, Epithelin precursor, GEP, gp88, Granulin, Granulin-epithelin, Granulins, PC cell-derived growth factor, PCDGF, PEPI, PGRN, Proepithelin, Progranulin
Target Sequences: NM_002087 NP_002078.1 P28799

Filtered by: None
Target
GRN / Granulin (99)
Reactivity
Human (83)
Mouse (26)
Rat (2)
Chimpanzee (3)
Gibbon (3)
Hamster (1)
Monkey (2)
Orangutan (3)
Application
IHC (28)
IHC-P (12)
WB (86)
ELISA (22)
ICC (2)
IF (3)
IP (11)
Peptide-ELISA (2)
Host
rabbit (74)
mouse (18)
goat (2)
guinea pig (1)
rat (4)
Isotype
IgG (22)
IgG1 (11)
IgG1,k (1)
IgG2a (5)
IgG2a,k (2)
Clonality
monoclonal mc (21)
polyclonal pc (78)
Clone
1F5 (1)
2A3C5 (1)
OTI1F9 (2)
OTI2D1 (2)
OTI2F4 (2)
OTI3B3 (2)
OTI3H6 (2)
OTI4B9 (2)
PG319-1 (1)
PG359-7 (1)
Format
AP Conjugated (2)
APC (4)
APC Conjugated (6)
Biotin Conjugated (10)
Carrier-free (6)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (9)
HRP Conjugated (8)
PE Conjugated (6)
Unconjugated (50)
Epitope
aa327-593 (12)
aa361-585 (10)
aa21-120 (8)
aa234-419 (8)
aa31-269 (8)
Internal (4)
aa232-281 (4)
C-Terminus (1)
aa18-589 (1)
aa20-310 (1)
aa248-259 (1)
aa257-269 (1)
aa563-591 (1)
Publications
No (99)
Showing 1-25 of 99 results

IHC-plus™ GRN / Granulin Antibody (C-Terminus) LS-B3158
Rabbit Polyclonal (IgG) to Human GRN / Granulin
Human
IHC, IHC-P, IP, WB
Unconjugated
50µg 0.25mg/ml  $485.00
Anti-GRN / Granulin antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

GRN / Granulin Antibody LS-C75078
Mouse Monoclonal (IgG2a) to Human GRN / Granulin
Human
ELISA, IP, WB
Unconjugated
100µg  $695.00

GRN / Granulin Antibody (aa257-269) LS-C112750
Goat Polyclonal to Human GRN / Granulin
Human
Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
GRN antibody (1 ug/ml) staining of HeLa lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

GRN / Granulin Antibody (clone 1F5) LS-C197353
Mouse Monoclonal [clone 1F5] (IgG2a,k) to Human GRN / Granulin
Human
ELISA, IF, WB
Unconjugated
100µg  $365.00
Immunofluorescence of monoclonal antibody to GRN on HeLa cell. [antibody concentration 10 ug/ml]
GRN monoclonal antibody (M01), clone 1F5 Western Blot analysis of GRN expression in HeLa.

GRN / Granulin Antibody LS-C144115
Rat Monoclonal (IgG2a) to Mouse GRN / Granulin
Mouse
ELISA
Unconjugated
500µg  $815.00

GRN / Granulin Antibody (aa248-259) LS-C154960
Goat Polyclonal to Human GRN / Granulin
Mouse, Rat, Hamster, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
GRN antibody (1 ug/ml) staining of A431 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

GRN / Granulin Antibody (aa31-269) LS-C294321
Rabbit Polyclonal to Mouse GRN / Granulin
Mouse
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $545.00
Western blot of recombinant GRN / Progranulin / Granulin.
Western Blot; Sample: Mouse Kidney lysate; Primary Ab: 2µg/ml Rabbit Anti-Mouse GRN Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

IHC-plus™ GRN / Granulin Antibody (aa21-120) LS-B14618
Rabbit Polyclonal to Human GRN / Granulin
Human
IHC, IHC-P, WB
Unconjugated
100µl 0.5mg/ml  $485.00
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot of recombinant GRN / Progranulin / Granulin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ GRN / Granulin Antibody LS-B12886
Guinea pig Polyclonal to Human GRN / Granulin
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $425.00
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis using anti-Progranulin (human), pAb at 1:2000 dilution. 1: Human Progranulin (FLAG-tagged) (50ng). 2: Human Progranulin (tag-free) (100ng). 3: Human Granulin C (FLAG-tagged) (50ng). 4: Human Granulin F (FLAG-tagged) (50ng). 5: Mouse Progranulin (FLAG-tagged) (50ng).6: Unrelated Protein (FLAG-tagged).

GRN / Granulin Antibody (clone PG359-7) LS-C344892
Mouse Monoclonal [clone PG359-7] (IgG1,k) to Human GRN / Granulin
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100µg  $355.00
Immunohistochemical staining of human tissue using anti-Progranulin (human), mAb (PG359-7) at 1:100 dilution. . A. Immunoperoxidase staining (cytoplasmic) of formalin-fixed, paraffin-embedded human cerebellum (200x, brown color). . B. Isotype control with IgG1 (negative control).
Immunoprecipitation of recombinant hProgranulin proteins using anti-Progranulin (human), mAb (PG359-7) . Recombinant hProgranulin Proteins were precipitated by PG359-7. The precipitated proteins were separated by SDS-PAGE, electroblotted, and visualized by Western blot/ECL reaction with rabbit anti-human Progranulin pAb.

GRN / Granulin Antibody LS-C806947
Rabbit Polyclonal (IgG) to Human GRN / Granulin
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

IHC-plus™ GRN / Granulin Antibody LS-B13393
Rabbit Polyclonal (IgG) to Human GRN / Granulin
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ GRN / Granulin Antibody (aa234-419) LS-B15005
Rabbit Polyclonal to Human GRN / Granulin
Human
IHC, IHC-P, WB
Unconjugated
50µl 0.5mg/ml  $425.00
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

GRN / Granulin Antibody (aa327-593, clone OTI1F9) LS-C340249
Mouse Monoclonal [clone OTI1F9] (IgG1) to Human GRN / Granulin
Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

GRN / Granulin Antibody (aa327-593, clone OTI1F9, Carrier-free) LS-C791204
Mouse Monoclonal [clone OTI1F9] (IgG1) to Human GRN / Granulin
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,

GRN / Granulin Antibody (aa327-593, clone OTI2F4) LS-C340286
Mouse Monoclonal [clone OTI2F4] (IgG1) to Human GRN / Granulin
Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Human Kidney tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

GRN / Granulin Antibody (aa327-593, clone OTI2F4, Carrier-free) LS-C791262
Mouse Monoclonal [clone OTI2F4] (IgG1) to Human GRN / Granulin
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,

GRN / Granulin Antibody LS-C665975
Rabbit Polyclonal (IgG) to Human GRN / Granulin
Human
ELISA, IHC, IP, WB
Unconjugated
100µg  $335.00

GRN / Granulin Antibody LS-C486786
Mouse Monoclonal to Human GRN / Granulin
Human
ELISA, ICC, IF
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00; 1ml  $1,335.00

GRN / Granulin Antibody (aa327-593, clone OTI2D1) LS-C794038
Mouse Monoclonal [clone OTI2D1] (IgG1) to Human GRN / Granulin
Human
IHC, WB
Unconjugated
100µl 1mg/ml  $345.00
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)

GRN / Granulin Antibody (aa327-593, clone OTI2D1, Carrier-free) LS-C791205
Mouse Monoclonal [clone OTI2D1] (IgG1) to Human GRN / Granulin
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)

GRN / Granulin Antibody (aa327-593, clone OTI4B9) LS-C794035
Mouse Monoclonal [clone OTI4B9] (IgG1) to Human GRN / Granulin
Human
IHC, WB
Unconjugated
100µl 1mg/ml  $345.00
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)

GRN / Granulin Antibody (aa327-593, clone OTI4B9, Carrier-free) LS-C798392
Mouse Monoclonal [clone OTI4B9] (IgG1) to Human GRN / Granulin
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)

GRN / Granulin Antibody (aa327-593, clone OTI3H6) LS-C794036
Mouse Monoclonal [clone OTI3H6] (IgG1) to Human GRN / Granulin
Human
IHC, WB
Unconjugated
100µl 1mg/ml  $345.00
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)

GRN / Granulin Antibody (aa327-593, clone OTI3H6, Carrier-free) LS-C798397
Mouse Monoclonal [clone OTI3H6] (IgG1) to Human GRN / Granulin
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-GRN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
Showing 1-25 of 99 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).