GRM6 / MGLUR6

glutamate receptor, metabotropic 6

Metabotropic Glutamate Receptor GRM6 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7, and GRM8. Group II and Group III receptors are linked to the inhibition of the cyclic AMP signaling cascade, but differ in their agonist selectivities.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

GRM6 / MGLUR6 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Human GRM6 / MGLUR6 Protein (Recombinant GST, N-terminus) (aa477-566) - LS-G58763

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GRM6 / MGLUR6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77334

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

95.3 kDa

Price:

20 µg/$215

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GRM6 / MGLUR6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122958

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

95.3 kDa

Price:

100 µg/$710

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