GRK6

G protein-coupled receptor kinase 6

Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).

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Products

Antibodies (43)

Type

Primary (43)

Target

GRK6 (43)

Reactivity

Human (43)

Mouse (16)

Rat (11)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (3)

Monkey (3)

Orangutan (3)

Rabbit (3)

Application

IHC (12)

IHC-P (5)

WB (42)

ELISA (13)

IF (8)

IP (1)

Peptide-ELISA (2)

Host

rabbit (41)

mouse (2)

Product Group

IHCPlus (1)

Isotype

IgG (25)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (42)

Clone

3B4 (1)

Format

APC (1)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (3)

Unconjugated (23)

Epitope

aa186-448 (8)

aa551-576 (7)

aa375-424 (4)

aa1-170 (2)

10-90 aa, N-terminal (1)

Asn22 (1)

N-Terminus (1)

aa10-59 (1)

aa382-417 (1)

aa526-576 (1)

Publications

No (43)

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GRK6 Antibody LS-C334672

Antibody:

GRK6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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GRK6 Antibody (N-Terminus) LS-C352269

Antibody:

GRK6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$299

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IHC-plus™ GRK6 Antibody LS-B10182

(4.0) Rating

Antibody:

GRK6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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GRK6 Antibody (aa1-170) LS-C375844

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa1-170) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

GRK6 Antibody (aa1-170) LS-C375843

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa1-170) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

GRK6 Antibody (aa551-576) LS-C327489

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa551-576) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

GRK6 Antibody (aa551-576, Biotin) LS-C219658

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa551-576) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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GRK6 Antibody (aa551-576, FITC) LS-C219659

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa551-576) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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GRK6 Antibody (aa551-576, APC) LS-C219657

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa551-576) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

GRK6 Antibody (aa551-576, PE) LS-C219661

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa551-576) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

GRK6 Antibody (aa551-576, Azide-free, HRP) LS-C219660

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa551-576) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

GRK6 Antibody (10-90 aa, N-terminal) LS-C383851

Antibody:

GRK6 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

GRK6 Antibody LS-C822732

Antibody:

GRK6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

GRK6 Antibody (aa10-59) LS-C118894

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa10-59) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

GRK6 Antibody LS-C804503

Antibody:

GRK6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

GRK6 Antibody (aa551-576) LS-C98906

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa551-576) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

GRK6 Antibody LS-C767018

Antibody:

GRK6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

GRK6 Antibody (Asn22) LS-C176764

Antibody:

GRK6 Rabbit anti-Human Polyclonal (Asn22) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

GRK6 Antibody (clone 3B4) LS-C197339

Antibody:

GRK6 Mouse anti-Human Monoclonal (3B4) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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GRK6 Antibody LS-C752495

Antibody:

GRK6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

GRK6 Antibody LS-C310520

Antibody:

GRK6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

GRK6 Antibody (aa375-424) LS-C151450

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa375-424) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

GRK6 Antibody (aa526-576) LS-C290932

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa526-576) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

GRK6 Antibody (aa186-448) LS-C374347

Antibody:

GRK6 Rabbit anti-Human Polyclonal (aa186-448) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

GRK6 Antibody LS-C490382

Antibody:

GRK6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

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