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GRK4

G protein-coupled receptor kinase 4

Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2.

Gene Name: G protein-coupled receptor kinase 4
Family/Subfamily: Protein Kinase , GPRK
Synonyms: GRK4, GPRK4, GPRK2L, GRK4a, IT11, ITI1
Target Sequences: NM_182982 NP_892027.2 P32298

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
GRK4 (5)
No (5)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
GRK4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
66.4 kDa
100 µg/$710
GRK4 Protein - Recombinant  G Protein Coupled Receptor Kinase 4 By SDS-PAGE
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E. coli
His-T7
33.8 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
GRK4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
66.4 kDa
20 µg/$215
GRK4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GRK4 Protein - Purified recombinant protein GRK4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
66.4 kDa
20 µg/$1,107
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).