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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GRIN2C / NMDAR2C / NR2C

glutamate receptor, ionotropic, N-methyl D-aspartate 2C

GRIN2C / NMDAR2C / NR2C is a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.

Gene Name: glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Family/Subfamily: Ion Channel , Glutamate receptor - ionotropic (NMDA receptor)
Synonyms: GRIN2C, GluN2C, NMDA receptor 2C, NMDAR2C, NR2C, GluR epsilon 3
Target Sequences: NM_000835 NP_000826.2 Q14957

Publications (2)

1
Salicylate enables cochlear arachidonic-acid-sensitive NMDA receptor responses. Ruel J, Chabbert C, Nouvian R, Bendris R, Eybalin M, Leger CL, Bourien J, Mersel M, Puel JL. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 28:7313-23. [PubMed:18632935]
2
Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms. Allen MA, Andrysik Z, Dengler VL, Mellert HS, Guarnieri A, Freeman JA, Sullivan KD, Galbraith MD, Luo X, Kraus WL, Dowell RD, Espinosa JM. eLife. 2014 3:e02200. (WB; Human) [PubMed:24867637] [PMC:PMC4033189] Related Antibodies: LS-C157785.

Viewing 1-25 of 41 items
GRIN2C / NMDAR2C / NR2C Antibody - Anti-GRIN2C / NMDAR2C antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human GRIN2C / NMDAR2C / NR2C
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
GRIN2C / NMDAR2C / NR2C Antibody - Anti-GRIN2C / NMDAR2C antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human GRIN2C / NMDAR2C / NR2C
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
HRP Conjugated
100µl   0.65mg/ml   $405.00
GRIN2C / NMDAR2C / NR2C Antibody - Anti-GRIN2C / NMDAR2C antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human GRIN2C / NMDAR2C / NR2C
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Biotin Conjugated
100µl   1mg/ml   $405.00
GRIN2C / NMDAR2C / NR2C Antibody - Anti-GRIN2C / NMDAR2C antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human GRIN2C / NMDAR2C / NR2C
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
FITC Conjugated
100µl   1mg/ml   $405.00
GRIN2C / NMDAR2C / NR2C Antibody - GRIN2C Antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The GRIN2C antibody detected the GRIN2C protein (arrow).
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(1) Publication(s)
Rabbit Polyclonal to Human GRIN2C / NMDAR2C / NR2C
Mouse, Human
WB
Unconjugated
400µl   $325.00
GRIN2C / NMDAR2C / NR2C Antibody - Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using GRIN2C Antibody at dilution of 1:100
Select
Rabbit Polyclonal (IgG) to Human GRIN2C / NMDAR2C / NR2C
Human
ELISA, IF, IHC
Unconjugated
50µg   4mg/ml   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human GRIN2C / NMDAR2C / NR2C
Human
ELISA
FITC Conjugated
50µg   $285.00; 100µg   0.25mg/ml   $385.00
Select
Rabbit Polyclonal (IgG) to Human GRIN2C / NMDAR2C / NR2C
Mouse, Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Mouse GRIN2C / NMDAR2C / NR2C
Mouse
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Mouse GRIN2C / NMDAR2C / NR2C
Mouse
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Mouse GRIN2C / NMDAR2C / NR2C
Mouse
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Mouse GRIN2C / NMDAR2C / NR2C
Mouse
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Mouse GRIN2C / NMDAR2C / NR2C
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Mouse GRIN2C / NMDAR2C / NR2C
Mouse
ELISA, WB
PE Conjugated
200µl   $740.00
GRIN2C / NMDAR2C / NR2C Antibody - Western blot analysis of NMDAR2C expression in SKOVCAR (A); HEK293T (B); SP2/0 (C) whole cell lysates.
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Rabbit Polyclonal to Human GRIN2C / NMDAR2C / NR2C
Mouse, Rat, Human
WB
Unconjugated
100µl   1mg/ml   $245.00
GRIN2C / NMDAR2C / NR2C Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human GRIN2C / NMDAR2C / NR2C
Human
ELISA, IHC, IHC-P
Unconjugated
60µl   $425.00
GRIN2C / NMDAR2C / NR2C Antibody
Select
Rabbit Polyclonal (IgG) to Human GRIN2C / NMDAR2C / NR2C
Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal (IgG) to Human GRIN2C / NMDAR2C / NR2C
Human
ELISA, IHC
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
GRIN2C / NMDAR2C / NR2C Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using GRIN2C Polyclonal Antibody at dilution of 1:100.
Select
Rabbit Polyclonal (IgG) to Human GRIN2C / NMDAR2C / NR2C
Human
ELISA, IHC
Unconjugated
20µl   0.4mg/ml   $205.00; 60µl   0.4mg/ml   $235.00; 120µl   0.4mg/ml   $295.00; 200µl   0.4mg/ml   $395.00
GRIN2C / NMDAR2C / NR2C Antibody - IHC of NMDA3 (P986) pAb in paraffin-embedded human brain tissue.
Select
Rabbit Polyclonal to Human GRIN2C / NMDAR2C / NR2C
Human
IHC, IHC-P
Unconjugated
100µl   $345.00
GRIN2C / NMDAR2C / NR2C Antibody - Immunohistochemistry analysis of NMDAε3 antibody in paraffin-embedded human brain tissue.
Select
Rabbit Polyclonal (IgG) to Human GRIN2C / NMDAR2C / NR2C
Human
IHC, Peptide-ELISA
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
GRIN2C / NMDAR2C / NR2C Antibody - Western blot of rat cerebellar lysate showing specific immunolabeling of the ~140k NR2C subunit of the NMDA Receptor.
Select
Rabbit Polyclonal to Rat GRIN2C / NMDAR2C / NR2C
Mouse, Rat, Human
IHC, WB
Unconjugated
10µg   $375.00
Select
Rabbit Polyclonal (IgG) to Human GRIN2C / NMDAR2C / NR2C
Human
IP, WB
Unconjugated
100µl   $605.00
Select
Rabbit Polyclonal (IgG) to Human GRIN2C / NMDAR2C / NR2C
Human
WB
Unconjugated
100µg   $605.00
Select
Rabbit Polyclonal to Human GRIN2C / NMDAR2C / NR2C
Mouse, Human
WB
Unconjugated
100µl   1mg/ml   $385.00

Viewing 1-25 of 41 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).