GRIA4 / GLUR4

glutamate receptor, ionotropic, AMPA 4

Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

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Proteins (1)

Type

Recombinant (1)

Target

GRIA4 / GLUR4 (1)

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No (1)

Tag

GST (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

Purification

Purified (1)

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Human GRIA4 / GLUR4 Protein (Recombinant GST) (Full Length) - LS-G28715

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

75.5 kDa

Price:

2 µg/$439

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