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GRB7

growth factor receptor-bound protein 7

Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress.

Gene Name: growth factor receptor-bound protein 7
Synonyms: GRB7, B47, GRB7 adapter protein
Target Sequences: NM_005310 NP_005301.2 Q14451

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Products
Antibodies (52)
Primary (52)
GRB7 (52)
Human (43)
Mouse (21)
Rat (13)
Bat (1)
Chicken (1)
Guinea pig (1)
Hamster (1)
Monkey (1)
Pig (1)
IHC (10)
IHC-P (6)
WB (48)
Flo (1)
ELISA (16)
IP (2)
Peptide-ELISA (2)
rabbit (45)
mouse (6)
goat (1)
Product Group
PathPlus Other (1)
IgG (21)
IgG1 (2)
IgG2b (2)
IgG2b,l (1)
monoclonal mc (5)
polyclonal pc (47)
3C12 (1)
OTI15E7 (2)
OTI6H2 (2)
APC (2)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (4)
Carrier-free (2)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (4)
Unconjugated (28)
aa298-489 (8)
aa66-327 (8)
aa289-318 (7)
aa233-532 (2)
C-Terminus (1)
N-Terminus (1)
aa1-140 (1)
aa1-532 (1)
aa124-141 (1)
aa176-192 (1)
aa25-38 (1)
aa30-100 (1)
aa35-201 (1)
No (52)
GRB7 Antibody
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GRB7 Rabbit anti-Human Polyclonal (aa35-201) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
GRB7 Antibody - Immunohistochemistry of paraffin-embedded human esophagus using antibody at 1:100 dilution.
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GRB7 Rabbit anti-Human Polyclonal (aa233-532) Antibody
Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
GRB7 Antibody - Western Blot analysis of GRB7 expression in transfected 293T cell line by GRB7 monoclonal antibody (M03), clone 3C12.Lane 1: GRB7 transfected lysate(59.7 KDa).Lane 2: Non-transfected lysate.
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GRB7 Mouse anti-Human Monoclonal (3C12) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$423
GRB7 Antibody - Western blot analysis of extracts of various cell lines.
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GRB7 Rabbit anti-Human Polyclonal (aa1-140) Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GRB7 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-GRB7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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GRB7 Mouse anti-Human Monoclonal (OTI6H2) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
GRB7 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-GRB7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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GRB7 Mouse anti-Human Monoclonal (Carrier-free) (OTI6H2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
GRB7 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
GRB7 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
GRB7 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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GRB7 Rabbit anti-Human Polyclonal (aa233-532) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
GRB7 Antibody - Anti-GRB7 antibody, IHC(P): Human Oesophagus Squama Cancer Tissue
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GRB7 Rabbit anti-Human Polyclonal (aa176-192) Antibody
Chicken, Pig, Bat, Guinea pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
GRB7 Antibody - IHC-P: GRB7 antibody testing of human esophagus squama cancer tissue
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GRB7 Rabbit anti-Human Polyclonal (aa124-141) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
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GRB7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
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GRB7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$341
GRB7 Antibody - Immunohistochemistry of paraffin-embedded Human brain using GRB7 Polyclonal Antibody at dilution of 1:40.
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GRB7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
GRB7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$379
Select
GRB7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$379
Select
GRB7 Rabbit anti-Human Polyclonal (aa289-318) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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GRB7 Rabbit anti-Human Polyclonal (aa289-318) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
GRB7 Rabbit anti-Human Polyclonal (aa289-318) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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GRB7 Rabbit anti-Human Polyclonal (aa289-318) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
GRB7 Rabbit anti-Human Polyclonal (aa289-318) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
GRB7 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY GRB7. (Right lane) cDNA for 48 hrs and lysed
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GRB7 Mouse anti-Human Monoclonal (OTI15E7) Antibody
Human
WB
Unconjugated
100 µl/$434
GRB7 Antibody - Immunohistochemical analysis of paraffin-embedded human-breast, antibody was diluted at 1:100.
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GRB7 Rabbit anti-Human Polyclonal (aa30-100) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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GRB7 Mouse anti-Human Polyclonal Antibody
Human
Flo, WB
Unconjugated
50 µg/$705
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GRB7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P
Unconjugated
100 µg/$357
GRB7 Antibody - Western blot analysis GRB7 using COLO205 whole cells lysates
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GRB7 Rabbit anti-Human Polyclonal Antibody
Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 52 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).