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GRB2

growth factor receptor-bound protein 2

Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.

Gene Name: growth factor receptor-bound protein 2
Synonyms: GRB2, Abundant SRC homology, Adapter protein GRB2, ASH, EGFRBP-GRB2, MST084, MSTP084, Protein Ash, SH2/SH3 adapter GRB2, Grb3-3, HT027, NCKAP2
Target Sequences: NM_002086 NP_002077.1 P62993

☰ Filters
Products
Proteins (18)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (5)
Recombinant (12)
GRB2 (18)
No (18)
6His, C-terminus (2)
6His, N-terminus (5)
GST (1)
GST, N-terminus (1)
His (2)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (16)
293F Cells (2)
293T Cells (2)
E. coli (6)
HEK 293 Cells (6)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (2)
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.3kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
GRB2 Protein - Purified recombinant protein GRB2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
25 kDa
20 µg/$1,107
GRB2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GRB2 Protein
Select
E. coli
6His, N-terminus
13 kDa
10 µg/$265; 200 µg/$484; 50 µg/$315
GRB2 Protein
Select
293F Cells
His
27.1 kDa
10 µg/$311; 50 µg/$502; 100 µg/$752
GRB2 Protein - Recombinant Growth Factor Receptor Bound Protein 2 By SDS-PAGE
Select
E. coli
His-T7
29.1 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Select
HEK 293 Cells
6His, N-terminus
28 kDa
100 µg/$298
GRB2 Protein
Select
E. coli
6His, N-terminus
10.8 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
GRB2 Protein - 12.5% SDS-PAGE of human GRB2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
49.61 kDa
10 µg/$479; 25 µg/$670
Select
HEK 293 Cells
6His, N-terminus
28 kDa
200 µl/$283
GRB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25 kDa
100 µg/$494
GRB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
20.4 kDa
100 µg/$494
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.3 kDa
10 µg/$317; 50 µg/$524
GRB2 Protein - Eukaryotic Growth Factor Receptor Bound Protein 2 (Grb2) by SDS-PAGE
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293F Cells
His, N-Terminal
27kDa
10 µg/$291; 50 µg/$502; 200 µg/$1,002; 100 µg/$802; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
GRB2 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
293T Cells
Myc-DDK (Flag)
25 kDa
20 µg/$150
GRB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
20.4 kDa
20 µg/$150
GRB2 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
HEK 293 Cells
6His, N-terminus
28 kDa
10 µg/$289; 5 µg/$262
Viewing 1-18 of 18 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).