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GRB14

growth factor receptor-bound protein 14

Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

Gene Name: growth factor receptor-bound protein 14
Synonyms: GRB14, GRB14 adapter protein, GRB 14
Target Sequences: NM_004490 NP_004481.2 Q14449

☰ Filters
Antibodies (21)
ELISA Kits (10)
Proteins (7)
Over-Expression Lysate (2)
Primary (21)
Recombinant (5)
Sandwich (9)
Sandwich CLIA (1)
GRB14 (38)
Human (20)
Mouse (9)
Rat (15)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
IHC (7)
IHC-P (4)
WB (16)
Flo (1)
ELISA (7)
ICC (1)
IF (3)
IP (1)
Peptide-ELISA (2)
rabbit (21)
Ig (1)
IgG (13)
polyclonal pc (21)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (8)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (15)
aa251-300 (4)
N-Terminus (2)
50-130 aa, Internal (1)
Asp123 (1)
Internal (1)
aa75-249 (1)
aa81-130 (1)
No (38)
Plasma (6)
Serum (6)
Tissue Homogenates (1)
GST, N-terminus (1)
His, N-Terminal (3)
Myc-DDK (Flag) (3)
Human (4)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (3)
GRB14 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
GRB14 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
Select
GRB14 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µl/$801
GRB14 Antibody
Select
GRB14 Rabbit anti-Human Polyclonal (aa75-249) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
GRB14 Antibody - Overlay histogram showing A549 cells stained with GRB14 Antibody (N-Term) (green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (GRB14 Antibody (N-Term), 1:25 dilution) for 60 min at 37°C. The secondary antibody used was Goat-Anti-Rabbit IgG,DyLight® 488 Conjugated Highly Cross-Adsorbed (1583138) at 1/200 dilution for 40 min at 37°C. Isotype control antibody (blue line) was rabbit IgG1 (1µg/1x10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
Select
GRB14 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$393
GRB14 Antibody - Western blot analysis of lysates from HUVEC, COLO, and MCF-7 cells, using GRB14 Antibody. The lane on the right is blocked with the synthesized peptide.
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GRB14 Rabbit anti-Human Polyclonal (aa81-130) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
GRB14 Antibody - Immunohistochemistry image at a dilution of 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
GRB14 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
GRB14 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
GRB14 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
GRB14 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
GRB14 Antibody - Immunochemical staining of human GRB14 in human gallbladder with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
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GRB14 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P
Unconjugated
100 µl/$412
GRB14 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
GRB14 Protein - Purified recombinant protein GRB14 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
60.8 kDa
20 µg/$1,107
GRB14 Antibody - Immunohistochemical analysis of GRB14 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
GRB14 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
Select
GRB14 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
GRB14 Antibody - Western blot of GRB14 antibody
Select
GRB14 Rabbit anti-Human Polyclonal (50-130 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GRB14 Antibody - Staining HuvEc cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
GRB14 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GRB14 Antibody - IHC of GRB14 (D123) pAb in paraffin-embedded human kidney tissue.
Select
GRB14 Rabbit anti-Human Polyclonal (Asp123) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
GRB14 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
GRB14 Antibody - Western blot analysis of extracts from COLO cells, HUVEC cells and MCF-7 cells, using GRB14 antibody.
Select
GRB14 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
GRB14 Antibody - Western blot analysis of extracts of human fetal intestine using GRB14 Polyclonal Antibody.
Select
GRB14 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
GRB14 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GRB14 Rabbit anti-Rat Polyclonal (aa251-300) Antibody
Rat
WB
Unconjugated
100 µl/$424
GRB14 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GRB14 Rabbit anti-Rat Polyclonal (aa251-300) (HRP) Antibody
Rat, Human
WB
HRP Conjugated
100 µl/$469
GRB14 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GRB14 Rabbit anti-Rat Polyclonal (aa251-300) (Biotin) Antibody
Rat, Human
WB
Biotin Conjugated
100 µl/$469
GRB14 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GRB14 Rabbit anti-Rat Polyclonal (aa251-300) (FITC) Antibody
Rat, Human
WB
FITC Conjugated
100 µl/$469
Viewing 1-25 of 38 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).