GPV / CD42d

glycoprotein V (platelet)

Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).

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Products

Proteins (2)

Type

Recombinant (2)

Target

GPV / CD42d (2)

Publications

No (2)

Tag

6His, N-terminus (1)

His-T7 (1)

Species

Human (1)

Mouse (1)

Source

E. coli (2)

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Mouse GPV / CD42d Protein (Recombinant 6His, N-terminus) (aa246-485) - LS-G13614

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

30.8 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human GPV / CD42d Protein (Recombinant His-T7) (aa17-242) - LS-G24267

Source:

E. coli

Tag:

His-T7

Molecular Weight:

25.6 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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