GPS2

G protein pathway suppressor 2

GPS2 is a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

GPS2 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human GPS2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65668

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.5 kDa

Price:

20 µg/$1,107

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Human GPS2 Protein (Recombinant GST, N-terminus) (aa228-327) - LS-G58740

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GPS2 Protein (Recombinant GST) (Full Length) - LS-G28706

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.71 kDa

Price:

2 µg/$439

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GPS2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100309

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.5 kDa

Price:

100 µg/$494

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Human GPS2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75998

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.5 kDa

Price:

20 µg/$150

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