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GPR3
G protein-coupled receptor 3
GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle where GPR3 maintains meiotic arrest in mouse oocytes. Oocytes from Gpr3 knockout mice resume meiosis within antral follicles, independently of an increase in luteinizing hormone, and this phenotype Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging (Ledent et al. 2005).
| Gene Name: | G protein-coupled receptor 3 |
| Family/Subfamily: | GPCR , Lysophospholipid/Lysosphingolipid |
| Synonyms: | GPR3, ACCA, ACCA orphan receptor, G protein-coupled receptor 3, GPCR3, Hacca, G-protein coupled receptor 3 |
| Target Sequences: | NM_005281 NP_005272.1 P46089 |
Publications (2)
1
Premature ovarian aging in mice deficient for Gpr3. Ledent C, Demeestere I, Blum D, Petermans J, Hmlinen T, Smits G, Vassart G. Proceedings of the National Academy of Sciences of the United States of America. 2005 102:8922-6. (ICC; Mouse)
[PubMed:15956199]
[PMC:PMC1150279]
Related Antibodies: LS-A121.
2
The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons. Thathiah A, Spittaels K, Hoffmann M, Staes M, Cohen A, Horr K, Vanbrabant M, Coun F, Baekelandt V, Delacourte A, Fischer DF, Pollet D, De Strooper B, Merchiers P. Science (New York, N.Y.). 2009 323:946-51. (IHC; Human)
[PubMed:19213921]
Related Antibodies: LS-A121.
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Neuroscience
GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Mouse, Rat, Hamster, Human, Monkey
ICC, IF, IHC, IHC-P
Unconjugated
50 µg/$440
Neuroscience
Fast Shipping
GPR3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
Neuroscience
GPR3 Mouse anti-Human Monoclonal (3B4-G3) Antibody
Human
ELISA, IHC, IHC-P, RNAi, WB
Unconjugated
50 µg/$460
GPR3 Goat anti-Human Polyclonal (aa229-238) Antibody
Rabbit, Mouse, Bovine, Rat, Hamster, Pig, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
Neuroscience
Fast Shipping
GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Rabbit, Bovine, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
GPR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
GPR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
GPR3 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
GPR3 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
GPR3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Fast Shipping
GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Pig, Human
IHC, IHC-P
Unconjugated
50 µg/$460
GPR3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
GPR3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated
50 µg/$294; 100 µg/$360
GPR3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
50 µg/$294; 100 µg/$360
GPR3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
50 µg/$294; 100 µg/$360
GPR3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$351
GPR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
GPR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GPR3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µg/$466
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