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GPR3

G protein-coupled receptor 3

GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle where GPR3 maintains meiotic arrest in mouse oocytes. Oocytes from Gpr3 knockout mice resume meiosis within antral follicles, independently of an increase in luteinizing hormone, and this phenotype Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging (Ledent et al. 2005).

Gene Name: G protein-coupled receptor 3
Family/Subfamily: GPCR , Lysophospholipid/Lysosphingolipid
Synonyms: GPR3, ACCA, ACCA orphan receptor, G protein-coupled receptor 3, GPCR3, Hacca, G-protein coupled receptor 3
Target Sequences: NM_005281 NP_005272.1 P46089

Publications (2)

1
Premature ovarian aging in mice deficient for Gpr3. Ledent C, Demeestere I, Blum D, Petermans J, Hmlinen T, Smits G, Vassart G. Proceedings of the National Academy of Sciences of the United States of America. 2005 102:8922-6. (ICC; Mouse) [PubMed:15956199] [PMC:PMC1150279] Related Antibodies: LS-A121.
2
The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons. Thathiah A, Spittaels K, Hoffmann M, Staes M, Cohen A, Horr K, Vanbrabant M, Coun F, Baekelandt V, Delacourte A, Fischer DF, Pollet D, De Strooper B, Merchiers P. Science (New York, N.Y.). 2009 323:946-51. (IHC; Human) [PubMed:19213921] Related Antibodies: LS-A121.

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Products
Antibodies (44)
Primary (44)
GPR3 (44)
Human (44)
Mouse (15)
Rat (15)
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Orangutan (3)
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IHC (35)
IHC-P (31)
WB (11)
ELISA (23)
ICC (7)
IF (8)
Peptide-ELISA (1)
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rabbit (41)
mouse (2)
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GPCR Database Antibodies (28)
IHCPlus (26)
PathPlus Neuro (4)
IgG (8)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (43)
3B4-G3 (1)
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APC Conjugated (4)
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HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (14)
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aa229-238 (1)
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GPR3 Antibody - Anti-GPR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Mouse, Rat, Hamster, Human, Monkey
ICC, IF, IHC, IHC-P
Unconjugated
50 µg/$440
GPR3 Antibody - Anti-GPR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) (Biotin) Antibody
Mouse, Rat, Hamster, Human, Monkey
ICC, IF, IHC, IHC-P
Biotin Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) (FITC) Antibody
Mouse, Rat, Hamster, Human, Monkey
ICC, IF, IHC, IHC-P
FITC Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) (AP) Antibody
Mouse, Rat, Hamster, Human, Monkey
ICC, IF, IHC, IHC-P
AP Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) (APC) Antibody
Mouse, Rat, Hamster, Human, Monkey
ICC, IF, IHC, IHC-P
APC Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) (PE) Antibody
Mouse, Rat, Hamster, Human, Monkey
ICC, IF, IHC, IHC-P
PE Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) (Azide-free) (HRP) Antibody
Mouse, Rat, Hamster, Human, Monkey
ICC, IF, IHC, IHC-P
HRP Conjugated, Azide-free
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
GPR3 Mouse anti-Human Monoclonal (3B4-G3) Antibody
Human
ELISA, IHC, IHC-P, RNAi, WB
Unconjugated
50 µg/$495
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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GPR3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Biotin Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human, Monkey
ELISA, IHC, IHC-P
FITC Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (N-Terminus) (AP) Antibody
Human, Monkey
ELISA, IHC, IHC-P
AP Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (N-Terminus) (APC) Antibody
Human, Monkey
ELISA, IHC, IHC-P
APC Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (N-Terminus) (Azide-free) (HRP) Antibody
Human, Monkey
ELISA, IHC, IHC-P
HRP Conjugated, Azide-free
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (N-Terminus) (PE) Antibody
Human, Monkey
ELISA, IHC, IHC-P
PE Conjugated
100 µl/$650
GPR3 Antibody - Antibody (0.3 ug/ml) staining of Human Brain (Frontal Cortex) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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GPR3 Goat anti-Human Polyclonal (aa229-238) Antibody
Rabbit, Mouse, Bovine, Rat, Hamster, Pig, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$451
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Rabbit, Bovine, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) (Biotin) Antibody
Rabbit, Bovine, Human, Monkey
ELISA, IHC, IHC-P
Biotin Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) (FITC) Antibody
Rabbit, Bovine, Human, Monkey
ELISA, IHC, IHC-P
FITC Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) (AP) Antibody
Rabbit, Bovine, Human, Monkey
ELISA, IHC, IHC-P
AP Conjugated
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) (Azide-free) (HRP) Antibody
Rabbit, Bovine, Human, Monkey
ELISA, IHC, IHC-P
HRP Conjugated, Azide-free
100 µl/$650
GPR3 Antibody - Anti-GPR3 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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GPR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
GPR3 Antibody - GPR3 antibody Western Blot of HCT15.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Human, Monkey
WB
Unconjugated
100 µl/$396
GPR3 Antibody - Anti-GPR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR3 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Pig, Human
IHC, IHC-P
Unconjugated
50 µg/$460
GPR3 Antibody - Immunohistochemistry of paraffin-embedded human adrenal gland tissue using antibody at 1:100 dilution.
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GPR3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$284; 100 µg/$351
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).