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GPC6 / Glypican 6

glypican 6

Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases (By similarity). Enhances migration and invasion of cancer cells through WNT5A signaling.

Gene Name: glypican 6
Synonyms: GPC6, Glypican proteoglycan 6, OMIMD1, Glypican 6, Glypican-6
Target Sequences: NM_005708 NP_005699.1 Q9Y625

Publications (2)

1
NFAT promotes carcinoma invasive migration through glypican-6. Gary K Yiu, Aura Kaunisto, Y Rebecca Chin, Alex Toker. The Biochemical journal. 2011 November;440:157-66. [Full Text Article] [PubMed:21871017] [PMC:PMC3204871] Related Antibodies: LS-C36518.
2
Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation. Fernando Salgado-Polo, Michiel van Veen, Bram van den Broek, Kees Jalink, Daniela Leyton-Puig, Anastassis Perrakis, Wouter H Moolenaar, Elisa Matas-Rico. Journal of cell science. 2020 Feb;133:jcs235044. [Full Text Article] [PubMed:31932507] [PMC:PMC7033719] Related Antibodies: LS-C36518.

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
GPC6 / Glypican 6 (3)
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His (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Yeast (1)
GPC6 / Glypican 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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Human GPC6 / Glypican 6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84903
293T Cells
Myc-DDK (Flag)
62.74 kDa
20 µg/$215
GPC6 / Glypican 6 Protein
Select
Human GPC6 / Glypican 6 Protein (Recombinant His) (aa24-529) - LS-G22940
Yeast
His
59.5 kD
1 mg/$1,607; 100 µg/$469; 20 µg/$349
GPC6 / Glypican 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
GPC6 / Glypican 6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100625
HEK 293 Cells
Myc-DDK (Flag)
62.74 kDa
100 µg/$710
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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