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GPC3 / Glypican 3

glypican 3

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Gene Name: glypican 3
Synonyms: GPC3, DGSX, Glypican proteoglycan 3, Glypican 3, Glypican-3, GTR2-2, Intestinal protein OCI-5, SGB, SGBS1, SGBS, MXR7, OCI-5, OCI5, SDYS, Secreted glypican-3, Heparan sulphate proteoglycan
Target Sequences: NM_004484 NP_004475.1 P51654

☰ Filters
Products
Proteins (22)
Over-Expression Lysate (6)
Recombinant (16)
GPC3 / Glypican 3 (22)
Bind (2)
ELISA (2)
Func (2)
SDS-PAGE (2)
No (22)
6His, C-terminus (4)
6His, N-terminus (1)
AVI-6His, C-terminus (1)
Fc, C-terminus (1)
GST, N-terminus (2)
His (2)
His,C-terminus (3)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (6)
Chimpanzee (1)
Human (13)
Mouse (3)
Rat (1)
Rhesus monkey (1)
293T Cells (3)
Baculovirus (1)
E. coli (3)
HEK 293 Cells (4)
Human (4)
Human Cells (1)
Mammalian Cells (3)
Wheat Germ Extract (2)
Yeast (1)
Purified (2)
Low endotoxin level (10)
Biologically active (4)
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
61.6kD
10 µg/$277; 50 µg/$395; 500 µg/$1,262; 1 mg/$1,627
GPC3 / Glypican 3 Protein - Recombinant Glypican 3 By SDS-PAGE
Select
E. coli
His-GST
56.5 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
GPC3 / Glypican 3 Protein
Select
Yeast
His
62.8 kD
1 mg/$1,683; 100 µg/$499; 20 µg/$364
GPC3 / Glypican 3 Protein - Recombinant Mouse Glypican-3/GPC3/OCI5 (C-6His)
Select
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
61.6 kDa
10 µg/$280; 50 µg/$419
GPC3 / Glypican 3 Protein
Select
Baculovirus
His,C-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant mouse GPC3 comprises 544 amino acids and has a predicted molecular mass of 62 kDa. The apparent molecular mass of the protein is approximately 62 kDa in SDS-PAGE under reducing conditions.
100 µg/$441; 1 mg/$2,003
GPC3 / Glypican 3 Protein - Measured by its binding ability in a functional ELISA. Immobilized human GPC3 at 5 µg/ml (100 µl/well) can bind human bFGF / FGF2 with a linear ranger of 0.156-2.5 ng/ml.
Select
HEK 293 Cells
His,C-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The secreted recombinant human GPC3 comprises 546 amino acids and has a predicted molecular mass of 62 kDa.
100 µg/$441; 1 mg/$1,991
GPC3 / Glypican 3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
2 µg/$439
GPC3 / Glypican 3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GPC3 / Glypican 3 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
6His, N-terminus
100 µg/$1,009; 20 µg/$431; 1 mg/$3,451
GPC3 / Glypican 3 Protein - Recombinant Glypican 3 By SDS-PAGE
Select
E. coli
His-T7
28.2 kDa
10 µg/$277; 50 µg/$420; 100 µg/$670; 200 µg/$837; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113
GPC3 / Glypican 3 Protein - Recombinant Human Glypican-3/GPC3/OCI5 (C-Fc)
Select
Human
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
87.7 kDa
10 µg/$277; 50 µg/$412
GPC3 / Glypican 3 Protein - Recombinant Human Glypican-3/GPC3/OCI5 (C-6His-Avi) Biotinylated
Select
Human
AVI-6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
63.4 kDa
20 µg/$416; 100 µg/$910
GPC3 / Glypican 3 Protein - Recombinant Rhesus Macaque Glypican-3/GPC3/OCI5 (C-6His)
Select
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
61.6 kDa
10 µg/$312; 50 µg/$515
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
61.6 kDa
10 µg/$277; 50 µg/$389
GPC3 / Glypican 3 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
61.6 kDa
50 µg/$453; 10 µg/$298; 1 mg/$2,064; 500 µg/$1,538
Select
E. coli
181 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
20.02 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
GPC3 / Glypican 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
63.73 kDa
100 µg/$494
GPC3 / Glypican 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
68.41 kDa
100 µg/$494
GPC3 / Glypican 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
68.41 kDa
20 µg/$150
GPC3 / Glypican 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
63.73 kDa
20 µg/$150
GPC3 / Glypican 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
65.62 kDa
20 µg/$150
GPC3 / Glypican 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
65.62 kDa
100 µg/$494
Viewing 1-22 of 22 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).