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GPBP1
GC-rich promoter binding protein 1
GPBP1 was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
| Gene Name: | GC-rich promoter binding protein 1 |
| Synonyms: | GPBP1, SSH6, Vascular wall-linked protein, GPBP, Vasculin |
| Target Sequences: | NM_022913 NP_075064.1 Q86WP2 |
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