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B001/B101
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20700 44th Avenue W
Lynnwood, WA 98036
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GPA33 / A33
glycoprotein A33 (transmembrane)
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
| Gene Name: | glycoprotein A33 (transmembrane) |
| Synonyms: | GPA33, A33, Cell surface A33 antigen, Glycoprotein A33, Transmembrane glycoprotein A33 |
| Target Sequences: | NM_005814 NP_005805.1 Q99795 |
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