GP1BB / CD42c

glycoprotein Ib (platelet), beta polypeptide

Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plateletes and megakaryocytes. A 411 amino acid protein arising from a longer, unspliced transcript in endothelial cells has been described; however, the authenticity of this product has been questioned. Yet another less abundant GPIb beta mRNA species of 3.5 kb, expressed in nonhematopoietic tissues such as endothelium, brain and heart, was shown to result from inefficient usage of a non-consensus polyA signal in the neighboring upstream gene (SEPT5, septin 5). In the absence of polyadenylation from its own imperfect site, the SEPT5 gene produces read-through transcripts that use the consensus polyA signal of this gene.

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Products

Antibodies (25)

Type

Primary (25)

Target

GP1BB / CD42c (25)

Reactivity

Human (9)

Mouse (14)

Rat (13)

Monkey (1)

Application

IHC (4)

IHC-P (4)

WB (23)

ELISA (3)

IP (1)

Peptide-ELISA (1)

Host

rabbit (24)

mouse (1)

Product Group

IHCPlus (2)

Isotype

IgG (4)

IgG2b (1)

Clonality

monoclonal mc (1)

polyclonal pc (24)

Format

APC (2)

APC Conjugated (2)

Biotin Conjugated (2)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (11)

Epitope

aa52-164 (8)

aa53-176 (8)

Internal (1)

Publications

No (24)

Yes (1)

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IHC-plus™ GP1BB / CD42c Antibody LS-B3174

(5.0) Rating

(1) Publication(s)

Antibody:

GP1BB / CD42c Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ GP1BB / CD42c Antibody LS-B4795

(4.0) Rating

Antibody:

GP1BB / CD42c Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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GP1BB / CD42c Antibody LS-C808185

Antibody:

GP1BB / CD42c Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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GP1BB / CD42c Antibody LS-C781542

Antibody:

GP1BB / CD42c Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

100 µg/$357

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GP1BB / CD42c Antibody LS-C675827

Antibody:

GP1BB / CD42c Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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GP1BB / CD42c Antibody LS-C813811

Antibody:

GP1BB / CD42c Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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GP1BB / CD42c Antibody (aa53-176) LS-C372645

Antibody:

GP1BB / CD42c Rabbit anti-Mouse Polyclonal (aa53-176) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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GP1BB / CD42c Antibody (aa53-176, HRP) LS-C708838

Antibody:

GP1BB / CD42c Rabbit anti-Mouse Polyclonal (aa53-176) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$335; 200 µl/$389; 500 µl/$566; 1 ml/$685; 2 ml/$922; 5 ml/$1,557

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GP1BB / CD42c Antibody (aa53-176, Biotin) LS-C419893

Antibody:

GP1BB / CD42c Rabbit anti-Mouse Polyclonal (aa53-176) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317

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GP1BB / CD42c Antibody (aa53-176, FITC) LS-C691793

Antibody:

GP1BB / CD42c Rabbit anti-Mouse Polyclonal (aa53-176) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676

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GP1BB / CD42c Antibody (aa53-176, APC) LS-C739311

Antibody:

GP1BB / CD42c Rabbit anti-Mouse Polyclonal (aa53-176) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395

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GP1BB / CD42c Antibody (aa53-176, APC, Cy7) LS-C731893

Antibody:

GP1BB / CD42c Rabbit anti-Mouse Polyclonal (aa53-176) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$497; 200 µl/$632; 500 µl/$1,132; 1 ml/$1,369; 2 ml/$1,916; 5 ml/$3,592

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GP1BB / CD42c Antibody (aa53-176, Cy3) LS-C699811

Antibody:

GP1BB / CD42c Rabbit anti-Mouse Polyclonal (aa53-176) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395

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GP1BB / CD42c Antibody (aa53-176, PE) LS-C722895

Antibody:

GP1BB / CD42c Rabbit anti-Mouse Polyclonal (aa53-176) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• APC, Cy7
• Cy3
• More...
  • PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • APC, Cy7
  • Cy3
  • PE

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GP1BB / CD42c Antibody LS-C341013

Antibody:

GP1BB / CD42c Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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GP1BB / CD42c Antibody LS-C496822

Antibody:

GP1BB / CD42c Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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GP1BB / CD42c Antibody (Internal) LS-C352252

Antibody:

GP1BB / CD42c Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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GP1BB / CD42c Antibody (aa52-164) LS-C294298

Antibody:

GP1BB / CD42c Rabbit anti-Rat Polyclonal (aa52-164) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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GP1BB / CD42c Antibody (aa52-164, HRP) LS-C708835

Antibody:

GP1BB / CD42c Rabbit anti-Rat Polyclonal (aa52-164) (HRP) Antibody

Reactivity:

Rat

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$335; 200 µl/$389; 500 µl/$566; 1 ml/$685; 2 ml/$922; 5 ml/$1,557

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GP1BB / CD42c Antibody (aa52-164, Biotin) LS-C685340

Antibody:

GP1BB / CD42c Rabbit anti-Rat Polyclonal (aa52-164) (Biotin) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317

Select

GP1BB / CD42c Antibody (aa52-164, FITC) LS-C691795

Antibody:

GP1BB / CD42c Rabbit anti-Rat Polyclonal (aa52-164) (FITC) Antibody

Reactivity:

Rat

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676

Select

GP1BB / CD42c Antibody (aa52-164, APC) LS-C739310

Antibody:

GP1BB / CD42c Rabbit anti-Rat Polyclonal (aa52-164) (APC) Antibody

Reactivity:

Rat

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395

Select

GP1BB / CD42c Antibody (aa52-164, APC, Cy7) LS-C731894

Antibody:

GP1BB / CD42c Rabbit anti-Rat Polyclonal (aa52-164) (APC, Cy7) Antibody

Reactivity:

Rat

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$497; 200 µl/$632; 500 µl/$1,132; 1 ml/$1,369; 2 ml/$1,916; 5 ml/$3,592

Select

GP1BB / CD42c Antibody (aa52-164, Cy3) LS-C699815

Antibody:

GP1BB / CD42c Rabbit anti-Rat Polyclonal (aa52-164) (Cy3) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395

Select

GP1BB / CD42c Antibody (aa52-164, PE) LS-C722894

Antibody:

GP1BB / CD42c Rabbit anti-Rat Polyclonal (aa52-164) (PE) Antibody

Reactivity:

Rat

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• APC, Cy7
• Cy3
• More...
  • PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • APC, Cy7
  • Cy3
  • PE

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