GP1BA / CD42b

glycoprotein Ib (platelet), alpha polypeptide

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

GP1BA / CD42b (8)

Publications

No (8)

Tag

10His, N-terminus + Myc, C-terminus (1)

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His, N-terminus (1)

His-S (1)

Myc-DDK (Flag) (2)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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Mouse GP1BA / CD42b Protein (Recombinant His-S) (aa17-282) - LS-G24213

Source:

E. coli

Tag:

His-S

Molecular Weight:

33.3 kDa

Price:

10 µg/$283; 50 µg/$457; 100 µg/$732; 200 µg/$912; 1 mg/$2,032; 500 µg/$1,567; 5 mg/$3,193; 2 mg/$2,219

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Human GP1BA / CD42b Protein (Recombinant His, N-terminus) (aa19-291) - LS-G24212

Source:

E. coli

Tag:

His, N-terminus

Molecular Weight:

34.0 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Human GP1BA / CD42b Protein (Recombinant 6His, N-terminus) (aa17-505) - LS-G20783

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

58 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human GP1BA / CD42b Protein (Recombinant GST, N-terminus) (aa19-128) - LS-G58726

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GP1BA / CD42b Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78101

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.7 kDa

Price:

20 µg/$215

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Human GP1BA / CD42b Protein (Recombinant GST) (Full Length) - LS-G28681

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

95.4 kDa

Price:

10 µg/$479; 25 µg/$670

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Human GP1BA / CD42b Protein (Recombinant 10His, N-terminus + Myc, C-terminus) - LS-G137035

Source:

E. coli

Tag:

10His, N-terminus + Myc, C-terminus

Molecular Weight:

15.9 kDa

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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GP1BA / CD42b Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123354

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.7 kDa

Price:

100 µg/$710

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