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GOPC / PIST
golgi-associated PDZ and coiled-coil motif containing
Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
| Gene Name: | golgi-associated PDZ and coiled-coil motif containing |
| Synonyms: | GOPC, CAL, CFTR-associated ligand, DJ94G16.2, DJ94G16.2 PIST, Fused in glioblastoma, GOPC1, FIG, PIST |
| Target Sequences: | NM_020399 NP_065132.1 Q9HD26 |
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