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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GOK / STIM1

stromal interaction molecule 1

GOK / STIM1 is a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: stromal interaction molecule 1
Synonyms: STIM1, D11S4896E, Stromal interaction molecule 1, GOK, STIM1L
Target Sequences: NM_003156 NP_003147.2 Q13586

Publications (2)

1
Neurokinin-neurotrophin interactions in airway smooth muscle. Meuchel LW, Stewart A, Smelter DF, Abcejo AJ, Thompson MA, Zaidi SI, Martin RJ, Prakash YS. American journal of physiology. Lung cellular and molecular physiology. 2011 301:L91-8. [PubMed:21515660] [PMC:PMC3129899]
2
Modification of STIM1 by O-linked N-acetylglucosamine (O-GlcNAc) attenuates store-operated calcium entry in neonatal cardiomyocytes. Zhu-Mauldin X, Marsh SA, Zou L, Marchase RB, Chatham JC. The Journal of biological chemistry. 2012 287:39094-106. (ICC; Human) [Full Text Article] [PubMed:22992728] Related Antibodies: LS-B1880.

Filtered By: None
Target
GOK / STIM1 (46)
Reactivity
Human (45)
Mouse (12)
Rat (21)
Bat (1)
Bovine (7)
Chicken (1)
Chimpanzee (3)
Dog (8)
Gibbon (3)
Guinea pig (2)
Hamster (1)
Horse (3)
Monkey (2)
Orangutan (1)
Rabbit (2)
Application
IHC (28)
IHC-P (11)
WB (40)
Flo (2)
ELISA (19)
ICC (3)
IF (3)
IP (6)
Peptide-ELISA (1)
Host
rabbit (41)
mouse (3)
goat (1)
sheep (1)
Isotype
IgG (27)
IgG1 (1)
IgG2a (1)
IgG2a,k (1)
Clonality
monoclonal mc (3)
polyclonal pc (43)
Clone
5A2 (1)
CDN3H4 (1)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Biotin Conjugated (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (21)
Epitope
aa1-211 (10)
aa509-538 (8)
C-Terminus (6)
aa611-660 (4)
N-Terminus (2)
aa600-685 (2)
aa231-243 (1)
aa45-74 (1)
aa550-600 (1)
aa635-685 (1)
Publications
No (45)
Yes (1)
Showing 1-25 of 46 results

GOK / STIM1 Antibody (C-Terminus, clone CDN3H4) IHC-plus™ LS-B1880
Publications (1)
Publications (1)
Mouse Monoclonal [clone CDN3H4] (IgG1) to Human GOK / STIM1
Mouse, Rat, Human
ICC IHC IHC-P IP WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-STIM1 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence staining of HeLa human cervix carcinoma cell line using anti-STIM1 (CDN3H4; methanol-aceton fixation; detection by Goat anti-mouse IgG1  598; red). Nuclei were stained with DAPI (blue).
Anti-STIM1 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence staining of HeLa human cervix carcinoma cell line using anti-STIM1 (CDN3H4; methanol-aceton fixation; detection by Goat anti-mouse IgG1  598; red). Nuclei were stained with DAPI (blue).

GOK / STIM1 Antibody (clone 5A2) IHC-plus™ LS-B4424
Mouse Monoclonal [clone 5A2] (IgG2a,k) to Human GOK / STIM1
Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg 0.5mg/ml  $485.00
Anti-STIM1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-STIM1 antibody IHC of human small intestine, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-STIM1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-STIM1 antibody IHC of human small intestine, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

GOK / STIM1 Antibody (N-Terminus) IHC-plus™ LS-B10815
Sheep Polyclonal to Human GOK / STIM1
Human
ELISA IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)

GOK / STIM1 Antibody (C-Terminus) IHC-plus™ LS-B1408
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-STIM1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Western blot of STIM1 in mouse thymus tissue lysate with STIM1 antibody at (A) 1 and (B) 2 ug/ml.
Anti-STIM1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Western blot of STIM1 in mouse thymus tissue lysate with STIM1 antibody at (A) 1 and (B) 2 ug/ml.

GOK / STIM1 Antibody (N-Terminus) IHC-plus™ LS-B10807
Rabbit Polyclonal to Human GOK / STIM1
Human
ELISA IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-GOK / STIM1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-GOK / STIM1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GOK / STIM1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-GOK / STIM1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GOK / STIM1 Antibody (aa231-243) LS-C154781
Goat Polyclonal to Human GOK / STIM1
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Horse, Bat, Human, Monkey
Peptide-ELISA WB
Unconjugated
100µg 0.5mg/ml  $405.00

GOK / STIM1 Antibody LS-C754777
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ELISA Flo IF IHC IP WB
Unconjugated
100µg  $355.00

GOK / STIM1 Antibody LS-C754776
Mouse Monoclonal (IgG2a) to Rat GOK / STIM1
Rat
ELISA Flo IF IHC IP WB
Unconjugated
100µg  $335.00

GOK / STIM1 Antibody (aa550-600) IHC-plus™ LS-B14252
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Mouse, Dog, Rat, Horse, Human
IHC IHC-P IP
Unconjugated
100µl 1mg/ml  $485.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

GOK / STIM1 Antibody LS-C489302
Rabbit Polyclonal to Human GOK / STIM1
Human
ELISA IHC IHC-P IP WB
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

GOK / STIM1 Antibody (aa45-74) LS-C357593
Rabbit Polyclonal to Human GOK / STIM1
Mouse, Rat, Orangutan, Human, Monkey
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $325.00
STIM1 antibody IHC-paraffin: Mouse Intestine Tissue.
STIM1 antibody IHC-paraffin: Rat Intestine Tissue.
STIM1 antibody IHC-paraffin: Mouse Intestine Tissue.
STIM1 antibody IHC-paraffin: Rat Intestine Tissue.

GOK / STIM1 Antibody LS-C490085
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µg  $365.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

GOK / STIM1 Antibody (aa509-538) LS-C325448
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ELISA IHC WB
Unconjugated
200µl  $530.00

GOK / STIM1 Antibody (aa509-538, HRP) LS-C540619
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ELISA IHC WB
HRP Conjugated
200µl  $680.00

GOK / STIM1 Antibody (aa509-538, Biotin) LS-C520476
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ELISA IHC WB
Biotin Conjugated
200µl  $680.00

GOK / STIM1 Antibody (aa509-538, FITC) LS-C217766
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ELISA IHC WB
FITC Conjugated
200µl  $680.00

GOK / STIM1 Antibody (aa509-538, AP) LS-C217764
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

GOK / STIM1 Antibody (aa509-538, APC) LS-C217765
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ELISA IHC WB
APC Conjugated
200µl  $680.00

GOK / STIM1 Antibody (aa509-538, PE) LS-C217767
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ELISA IHC WB
PE Conjugated
200µl  $680.00

GOK / STIM1 Antibody LS-C679677
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ELISA IHC IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human lymph node tissue at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lymph node tissue at dilution of 1:100

GOK / STIM1 Antibody (aa509-538) LS-C161558
Rabbit Polyclonal to Human GOK / STIM1
Human
IHC IHC-P WB
Unconjugated
400µl  $305.00
STIM1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
STIM1 Antibody western blot of CEM cell line lysates (35 ug/lane). The STIM1 antibody detected the STIM1 protein (arrow).
STIM1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
STIM1 Antibody western blot of CEM cell line lysates (35 ug/lane). The STIM1 antibody detected the STIM1 protein (arrow).

GOK / STIM1 Antibody (aa1-211) LS-C374717
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Rat, Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of GOK / STIM1 antibody.
Western blot of GOK / STIM1 antibody.

GOK / STIM1 Antibody (aa1-211, FITC) LS-C422789
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $395.00

GOK / STIM1 Antibody (aa1-211, FITC) LS-C694361
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Rat, Human
IHC WB
FITC Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western blot of GOK / STIM1 antibody.
Western blot of GOK / STIM1 antibody.

GOK / STIM1 Antibody (aa600-685) LS-C76130
Rabbit Polyclonal (IgG) to Human GOK / STIM1
Human
ELISA WB
Unconjugated
100µl  $515.00
Showing 1-25 of 46 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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