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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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GNS
glucosamine (N-acetyl)-6-sulfatase
The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
| Gene Name: | glucosamine (N-acetyl)-6-sulfatase |
| Synonyms: | GNS, Glucosamine-6-sulfatase, G6S |
| Target Sequences: | NM_002076 NP_002067.1 P15586 |
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