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GnRH receptor / GNRHR

gonadotropin-releasing hormone receptor

GnRH receptor / GNRHR is the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Gene Name: gonadotropin-releasing hormone receptor
Family/Subfamily: GPCR , Releasing hormone
Synonyms: GNRHR, GnRH receptor, GnRH-R, GRHR, HH7, LHRHR, LRHR, Luliberin receptor, Type I GnRH receptor, GNRHR1, Lh-rh receptor
Target Sequences: NM_000406 NP_000397.1 P30968

Publications (1)

1
The E3 ubiquitin ligase RNF216/TRIAD3 is a key coordinator of the hypothalamic-pituitary-gonadal axis. Arlene J George, Bin Dong, Hannah Lail, Morgan Gomez, Yarely C Hoffiz, Christopher B Ware, Ning Fang, Anne Z Murphy, Erik Hrabovszky, Desiree Wanders, Angela M Mabb. iScience. 2022 June;25:104386. [Full Text Article] [PubMed:35620441] [PMC:PMC9126796] Related Antibodies: LS-C383737.

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GnRH receptor / GNRHR (11)
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GnRH receptor / GNRHR ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GnRH receptor / GNRHR ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.39 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GnRH receptor / GNRHR ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GnRH receptor / GNRHR ELISA Kit
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Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
GnRH receptor / GNRHR ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
GnRH receptor / GNRHR ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
GnRH receptor / GNRHR ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
GnRH receptor / GNRHR ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
GnRH receptor / GNRHR ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
GnRH receptor / GNRHR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
GnRH receptor / GNRHR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.39 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).