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GNLY / Granulysin

granulysin

GNLY / Granulysin is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: granulysin
Synonyms: GNLY, 519, Granulysin, LAG2, LAG-2, Protein NKG5, Lymphocyte-activation gene 2, T-cell activation protein 519, TLA519, NKG5, D2S69E, Lymphokine LAG-2
Target Sequences: NM_012483 NP_036615.2 P22749

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).