GNL3L

guanine nucleotide binding protein-like 3 (nucleolar)-like

Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

GNL3L (4)

Publications

No (4)

Tag

GST (1)

His-SUMO (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human GNL3L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91119

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.4 kDa

Price:

20 µg/$150

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GNL3L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111462

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.4 kDa

Price:

100 µg/$494

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Human GNL3L Protein (Recombinant His-SUMO) (Full Length) - LS-G21928

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

81.53 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human GNL3L Protein (Recombinant GST) (Full Length) - LS-G34010

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

92 kDa

Price:

10 µg/$479; 25 µg/$670

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