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May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.
Gene Name: | guanine nucleotide binding protein-like 3 (nucleolar) |
Synonyms: | GNL3, C77032, E2-induced gene 3 protein, E2IG3, NS, NNP47, Nucleostemin, Novel nucleolar protein 47 |
Target Sequences: | NM_014366 NP_055181.3 Q9BVP2 |
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