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Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K+ channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
Gene Name: | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 |
Synonyms: | GNAI3, 87U6, ARCND1, G(i) alpha-3 |
Target Sequences: | NM_006496 NP_006487.1 P08754 |
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