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GNAI2

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division.Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool.

Gene Name: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Synonyms: GNAI2, H_LUCA16.1, GNAI2B, H_LUCA15.1
Target Sequences: NM_002070 NP_002061.1 P04899

Publications (1)

1
Suppressor of Fused restraint of Hedgehog activity level is critical for osteogenic proliferation and differentiation during calvarial bone development. Jianying Li, Ying Cui, Jie Xu, Qihui Wang, Xueqin Yang, Yan Li, Xiaoyun Zhang, Mengsheng Qiu, Ze Zhang, Zunyi Zhang. The Journal of biological chemistry. 2017 September;292:15814-15825. [Full Text Article] [PubMed:28794157] [PMC:PMC5612112]

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GNAI2 ELISA Kit
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0.312 - 20 ng/ml
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).