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GNAI1 / Gi
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
| Gene Name: | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| Synonyms: | GNAI1, Gi1 protein alpha subunit, Gi |
| Target Sequences: | NM_002069 NP_002060.4 P63096 |
Publications (2)
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