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GM2A

GM2 ganglioside activator

The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

Gene Name: GM2 ganglioside activator
Synonyms: GM2A, Ganglioside GM2 activator, GM2 ganglioside activator, GM2-AP, SAP-3
Target Sequences: NM_000405 NP_000396.2 P17900

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Products
Proteins (12)
Over-Expression Lysate (4)
Recombinant (8)
GM2A (12)
No (12)
6His, C-terminus (2)
GST (2)
GST, N-terminus (1)
His,C-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (10)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Human Cells (1)
Insect Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (3)
GM2A Protein - Purified recombinant protein GM2A was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
20.7 kDa
20 µg/$1,107
GM2A Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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E. coli
GST
45 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
GM2A Protein - Recombinant  GM2 Ganglioside Activator By SDS-PAGE
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E. coli
His-T7
22.2 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
GM2A Protein - 12.5% SDS-PAGE of human GM2A stained with Coomassie Blue
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Wheat Germ Extract
GST
47.2 kDa
10 µg/$479; 25 µg/$670
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
18.6kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
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Insect Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
19.8 kDa
50 µg/$854
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
18.6 kDa
10 µg/$317; 50 µg/$524
GM2A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
20.6 kDa
100 µg/$494
GM2A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
20.7 kDa
100 µg/$494
Select
293T Cells
Myc-DDK (Flag)
20.7 kDa
20 µg/$150
GM2A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
20.6 kDa
20 µg/$150
Viewing 1-12 of 12 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).