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GM2A
GM2 ganglioside activator
The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
| Gene Name: | GM2 ganglioside activator |
| Synonyms: | GM2A, Ganglioside GM2 activator, GM2 ganglioside activator, GM2-AP, SAP-3 |
| Target Sequences: | NM_000405 NP_000396.2 P17900 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
