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GLUL / Glutamine Synthetase

glutamate-ammonia ligase

GLUL / Glutamine Synthetase belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

Gene Name: glutamate-ammonia ligase
Synonyms: GLUL, GLNS, Glutamate decarboxylase, Glutamate-ammonia ligase, Glutamine synthase, GS, Glutamate--ammonia ligase, Glutamine synthetase, PIG43, PIG59
Target Sequences: NM_002065 NP_002056.2 P15104

Publications (3)

1
GLUL Ablation Can Confer Drug Resistance to Cancer Cells via a Malate-Aspartate Shuttle-Mediated Mechanism. Magesh Muthu, Ranjeet Kumar, Azharuddin Sajid Syed Khaja, Jonathan D Gilthorpe, Jenny L Persson, Anders Nordström. Cancers. 2019 Dec;11:1945. [Full Text Article] [PubMed:31817360] [PMC:PMC6966511] Related Antibodies: LS-C114787.
2
Toll-Like Receptor 9-Mediated Neuronal Innate Immune Reaction Is Associated with Initiating a Pro-Regenerative State in Neurons of the Dorsal Root Ganglia Non-Associated with Sciatic Nerve Lesion. Petr Dubový, Ivana Hradilová-Svíženská, Václav Brázda, Marek Joukal. International journal of molecular sciences. 2021 July;22:7446. [Full Text Article] [PubMed:34299065] [PMC:PMC8304752] Related Antibodies: LS-B2579.
3
Bilateral elevation of interleukin-6 protein and mRNA in both lumbar and cervical dorsal root ganglia following unilateral chronic compression injury of the sciatic nerve. Dubov[Character fd] P, Br[Character e1]zda V, Klus[Character e1]kov[Character e1] I, Hradilov[Character e1]-Sv[Character ed]ensk[Character e1] I. Journal of neuroinflammation. 2013 10:55. [Full Text Article] [PubMed:23634725] [PMC:PMC3657546] Related Antibodies: LS-B2579.

☰ Filters
Products
ELISA Kits (13)
Custom (5)
Sandwich (7)
Sandwich CLIA (1)
GLUL / Glutamine Synthetase (13)
Human (3)
Mouse (3)
Rat (2)
Bovine (1)
Chicken (1)
Dog (1)
Pig (1)
Rabbit (1)
96-Well Strip Plate (13)
No (13)
Cell Lysates (1)
Plasma (7)
Serum (7)
Tissue Homogenates (3)
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
0.27 - 200 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$990
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$854
GLUL / Glutamine Synthetase ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$893
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GLUL / Glutamine Synthetase ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
GLUL / Glutamine Synthetase ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
GLUL / Glutamine Synthetase ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
GLUL / Glutamine Synthetase ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
GLUL / Glutamine Synthetase ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
GLUL / Glutamine Synthetase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Viewing 1-13 of 13 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).