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GLRX3 / Glutaredoxin 3

glutaredoxin 3

Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). Crucial regulator of cellular iron homeostasis and hemoglobin maturation. May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.

Gene Name: glutaredoxin 3
Synonyms: GLRX3, BA500G10.4, Glutaredoxin-3, GRX3, GLRX4, Glutaredoxin 4, PICOT, Thioredoxin-like protein 2, Thioredoxin-like, Thioredoxin-like 2, TXNL2, TXNL3, Glutaredoxin 3, GRX4, PKC-theta-interacting protein, PKCq-interacting protein
Target Sequences: NM_006541 NP_006532.2 O76003

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).