GLRX2 / Glutaredoxin 2

glutaredoxin 2

Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

GLRX2 / Glutaredoxin 2 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

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GLRX2 / Glutaredoxin 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112886

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.5 kDa

Price:

100 µg/$494

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Human GLRX2 / Glutaredoxin 2 Protein (Recombinant GST) (Full Length) - LS-G33588

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

39.38 kDa

Price:

10 µg/$479; 25 µg/$670

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Human GLRX2 / Glutaredoxin 2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68411

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.5 kDa

Price:

20 µg/$1,107

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Human GLRX2 / Glutaredoxin 2 Protein (Recombinant GST, N-terminus) (aa1-124) - LS-G56954

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human GLRX2 / Glutaredoxin 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82127

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.5 kDa

Price:

20 µg/$150

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Human GLRX2 / Glutaredoxin 2 Protein (Recombinant His) - LS-G656

Source:

E. coli

Tag:

His

Price:

100 µg/$342; 500 µg/$641; 20 µg/$254

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