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GLO1 / Glyoxalase I

glyoxalase I

Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis.

Gene Name:	glyoxalase I
Synonyms:	GLO1, Aldoketomutase, Glx I, Glyoxalase domain containing 1, Glyoxalase I, Lactoyl glutathione lyase, Lactoylglutathione lyase, GLOD1, Methylglyoxalase, Ketone-aldehyde mutase, GLYI
Target Sequences:	NM_006708 NP_006699.2 Q04760

Publications (2)

Glyoxalase I activity and immunoreactivity in the aging human lens. Mailankot M, Padmanabha S, Pasupuleti N, Major D, Howell S, Nagaraj RH. Biogerontology. 2009 10:711-20. [PubMed:19238574] [PMC:PMC3560407]

Opposing roles of RAGE and Myd88 signaling in extensive liver resection. Zeng S, Zhang QY, Huang J, Vedantham S, Rosario R, Ananthakrishnan R, Yan SF, Ramasamy R, DeMatteo RP, Emond JC, Friedman RA, Schmidt AM. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012 26:882-93. [PubMed:22075646] [PMC:PMC3365861]

Glyoxalase I (GLO-1) Assay Kit (Colorimetric) - LS-K216

Type:

Detection/Quantition

Target:

GLO1 / Glyoxalase I

Application:

Spectrophotometry (visible)

Price:

100 Tests/$515

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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