Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions,
rewards, and special promotions.
Unfortunately, the antibody (ID:162612) is no longer available.
Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page.
Please contact us if you have any questions.
GLI / GLI1
GLI family zinc finger 1
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
GLI family zinc finger 1
GLI1, Gli-1, GLI family zinc finger 1, Glioma-associated oncogene, Glioma-associated oncogene 1, Oncogene GLI, GLI, Zinc finger protein GLI1
Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis. Niemann C, Unden AB, Lyle S, Zouboulis ChC, Toftgrd R, Watt FM. Proceedings of the National Academy of Sciences of the United States of America. 2003 11873-80.
Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment. Qualtrough D, Buda A, Gaffield W, Williams AC, Paraskeva C. International journal of cancer. Journal international du cancer. 2004 110:831-7.
Hedgehog signaling drives cellular survival in human colon carcinoma cells. Mazumdar T, DeVecchio J, Shi T, Jones J, Agyeman A, Houghton JA. Cancer research. 2011 71:1092-102. (WB; Human)
Expression of hedgehog pathway components in prostate carcinoma microenvironment: shifting the balance towards autocrine signalling. Tzelepi V, Karlou M, Wen S, Hoang A, Logothetis C, Troncoso P, Efstathiou E. Histopathology. 2011 58:1037-47. (IHC; Human)
Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells. Mazumdar T, Devecchio J, Agyeman A, Shi T, Houghton JA. Cancer research. 2011 71:5904-14.
Hedgehog signaling inhibition by the small molecule smoothened inhibitor GDC-0449 in the bone forming prostate cancer xenograft MDA PCa 118b. Karlou M, Lu JF, Wu G, Maity S, Tzelepi V, Navone NM, Hoang A, Logothetis CJ, Efstathiou E. The Prostate. 2012 72:1638-47. (IHC; Human)