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GLDC

glycine dehydrogenase (decarboxylating)

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Gene Name: glycine dehydrogenase (decarboxylating)
Synonyms: GLDC, GCSP, Glycine decarboxylase, HYGN1, GCE, Glycine dehydrogenase, NKH
Target Sequences: NM_000170 NP_000161.2 P23378

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
GLDC (6)
No (6)
GST, N-terminus (1)
His (2)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (1)
GLDC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
112.73 kDa
100 µg/$494
GLDC Protein - Recombinant  Glycine Dehydrogenase By SDS-PAGE
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E. coli
His-T7
30.4 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
GLDC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
112.73 kDa
20 µg/$150
GLDC Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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E. coli
His
22.7 kDa
10 µg/$296; 50 µg/$537; 100 µg/$860; 200 µg/$1,057; 1 mg/$2,229; 500 µg/$1,745; 5 mg/$3,753; 2 mg/$2,420
GLDC Protein - Recombinant Glycine Dehydrogenase By SDS-PAGE
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E. coli
His
23.5 kDa
10 µg/$296; 50 µg/$537; 100 µg/$860; 200 µg/$1,057; 1 mg/$2,229; 500 µg/$1,745; 5 mg/$3,753; 2 mg/$2,420
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).