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B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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GLB1 / Beta-Galactosidase
galactosidase, beta 1
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.Isoform 2 has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers.
| Gene Name: | galactosidase, beta 1 |
| Synonyms: | GLB1, Acid beta-galactosidase, Beta-galactosidase, Elastin receptor 1, Elastin receptor 1 (67kD), Elastin receptor 1, 67kDa, Galactosidase, beta 1, ELNR1, Lactase, MPS4B |
| Target Sequences: | NM_000404 NP_000395.2 P16278 |
Publications (5)
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