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GJA1 / CX43 / Connexin 43

gap junction protein, alpha 1, 43kDa

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract.

Gene Name: gap junction protein, alpha 1, 43kDa
Family/Subfamily: Ion Channel , Connexin
Synonyms: GJA1, Connexin-43, DFNB38, Connexin 43, Gap junction alpha-1 protein, GJAL, HSS, Gap junction protein alpha 1, ODDD, ODD, AVSD3, CX43, HLHS1, ODOD, SDTY3
Target Sequences: NM_000165 NP_000156.1 P17302

Publications (4)

1
Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex. Liu X, Sun L, Torii M, Rakic P. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:8280-5. [PubMed:22566616] [PMC:PMC3361458] Related Antibodies: LS-C97725.
2
Inhibition of Connexin 43 and Phosphorylated NR2B in Spinal Astrocytes Attenuates Bone Cancer Pain in Mice. Yang H, Yan H, Li X, Liu J, Cao S, Huang B, Huang D, Wu L. Frontiers in cellular neuroscience. 2018 May;12:129. (Rat) [Full Text Article] [PubMed:29867362] [PMC:PMC5951934] Related Antibodies: LS-B9771.
3
Structural alterations and inflammation in the heart after multiple trauma followed by reamed versus non-reamed femoral nailing. Meike Baur, Birte Weber, Ina Lackner, Florian Gebhard, Roman Pfeifer, Paolo Cinelli, Sascha Halvachizadeh, Michel Teuben, Miriam Lipiski, Nikola Cesarovic, Hans-Christoph Pape, Miriam Kalbitz. PloS one. 2020 June;15:e0235220. [Full Text Article] [PubMed:32584885] [PMC:PMC7316303]
4
Engineered bacterial voltage-gated sodium channel platform for cardiac gene therapy. Hung X Nguyen , Tianyu Wu , Daniel Needs, Hengtao Zhang, Robin M Perelli, Sophia DeLuca, Rachel Yang, Michael Tian, Andrew P Landstrom, Craig Henriquez, Nenad Bursac. Nature communications. 2022 February;13:620. [Full Text Article] [PubMed:35110560] [PMC:PMC8810800] Related Antibodies: LS-B9770.
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ELISA Kits (30)
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Sandwich CLIA (3)
GJA1 / CX43 / Connexin 43 (30)
Human (8)
Mouse (8)
Rat (8)
Chicken (2)
Dog (1)
Guinea pig (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
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12 x 8-Well Microstrips (3)
96-Well Microplate (5)
96-Well Strip Plate (22)
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Yes (1)
Adherent Cell Cultures (2)
Cell Lysates (3)
Plasma (13)
Serum (13)
Tissue Homogenates (6)
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
GJA1 / CX43 / Connexin 43 ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$772
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$782
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$764
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
GJA1 / CX43 / Connexin 43 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
GJA1 / CX43 / Connexin 43 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).